Strong SARS-CoV-2 N-Specific CD8<sup>+</sup> T Immunity Induced by Engineered Extracellular Vesicles Associates with Protection from Lethal Infection in Mice

Strong SARS-CoV-2 N-Specific CD8<sup>+</sup> T Immunity Induced by Engineered Extracellular Vesicles Associates with Protection from Lethal Infection in Mice

SARS-CoV-2-specific CD8<sup>+</sup> T cell immunity is expected to counteract viral variants in both efficient and durable ways. We recently described a way to induce a potent SARS-CoV-2 CD8<sup>+</sup> T immune response through the generation of engineered extracellular vesi...

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Bibliographic Details
Main Authors: Flavia Ferrantelli, Chiara Chiozzini, Francesco Manfredi, Patrizia Leone, Massimo Spada, Antonio Di Virgilio, Andrea Giovannelli, Massimo Sanchez, Andrea Cara, Zuleika Michelini, Maurizio Federico
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
SARS-CoV-2
vaccines
CD8<sup>+</sup> T cell immunity
extracellular vesicles
Nef
Online Access:https://www.mdpi.com/1999-4915/14/2/329

Internet

https://www.mdpi.com/1999-4915/14/2/329

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