Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding

Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding

The role of the primary cilium in key signaling pathways depends on dynamic regulation of ciliary membrane protein composition, yet we know little about the motors or membrane events that regulate ciliary membrane protein trafficking in existing organelles. Recently, we showed that cilium-generated...

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Bibliographic Details
Main Authors: Muqing Cao, Jue Ning, Carmen I Hernandez-Lara, Olivier Belzile, Qian Wang, Susan K Dutcher, Yanjie Liu, William J Snell
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-02-01
Series:eLife
Subjects:
Chlamydomonas
ciliary signaling
ciliary ectosome
intraflagellar transport
cytoplasmic dynein
membrane protein trafficking
Online Access:https://elifesciences.org/articles/05242

Internet

https://elifesciences.org/articles/05242

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