Isolated familial somatotropinoma: 11Q13-LOH and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesis

Isolated familial somatotropinoma: 11Q13-LOH and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesis

OBJECTIVE: Non-pituitary tumors have been reported in a subset of patients harboring germline mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene. However, no detailed investigations of non-pituitary tumors of AIP-mutated patients have been reported so far. PATIENTS: We examine...

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Bibliographic Details
Main Authors: Rodrigo A. Toledo, Berenice B. Mendonca, Maria Candida B. V. Fragoso, Iberê C. Soares, Madson Q. Almeida, Michelle B. Moraes, Delmar M. Lourenço-Jr, Venâncio A. F. Alves, Marcello D. Bronstein, Sergio P. A. Toledo
Format: Article
Language:English
Published: Elsevier España 2010-01-01
Series:Clinics
Subjects:
Acromegaly
pituitary tumor
FIPA
AIP
Adrenocortical tumor
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322010000400010

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322010000400010

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