WASp Is Essential for Effector-to-Memory conversion and for Maintenance of CD8+T Cell Memory

Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency characterized by recurrent infections, micro thrombocytopenia, eczema, and a high incidence of autoimmunity and malignancy. A defect in the T cell compartment is thought to be a major cause of immunodeficiency in patients wit...

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Bibliographic Details
Main Authors: Qiao Liu, Liang Zhang, Zhou Shu, Tingting Yu, Lina Zhou, Wenxia Song, Xiaodong Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02262/full