Metabolic engineering of the thermophilic filamentous fungus Myceliophthora thermophila to produce fumaric acid

Metabolic engineering of the thermophilic filamentous fungus Myceliophthora thermophila to produce fumaric acid

Abstract Background Fumaric acid is widely used in food and pharmaceutical industries and is recognized as a versatile industrial chemical feedstock. Increasing concerns about energy and environmental problems have resulted in a focus on fumaric acid production by microbial fermentation via bioconve...

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Bibliographic Details
Main Authors: Shuying Gu, Jingen Li, Bingchen Chen, Tao Sun, Qian Liu, Dongguang Xiao, Chaoguang Tian
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Biotechnology for Biofuels
Subjects:
Myceliophthora thermophila
Metabolic engineering
Fumaric acid
Reductive TCA
CRISPR/Cas9
Online Access:http://link.springer.com/article/10.1186/s13068-018-1319-1

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http://link.springer.com/article/10.1186/s13068-018-1319-1

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