The Role of Chaperone-Mediated Autophagy in Bortezomib Resistant Multiple Myeloma

The Role of Chaperone-Mediated Autophagy in Bortezomib Resistant Multiple Myeloma

<b>Background:</b> Multiple myeloma (MM) remains incurable despite high-dose chemotherapy, autologous stem cell transplants and novel agents. Even with the improved survival of MM patients treated with novel agents, including bortezomib (Bz), the therapeutic options in relapsed/refractor...

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Bibliographic Details
Main Authors: Nicholas Nikesitch, Patricia Rebeiro, Lye Lin Ho, Srinivasa Pothula, Xin Maggie Wang, Tiffany Khong, Hazel Quek, Andrew Spencer, Cheok Soon Lee, Tara L. Roberts, Silvia C. W. Ling
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
multiple myeloma
resistance
bortezomib
chaperone mediated autophagy
LAMP2A
ER stress and autophagy
Online Access:https://www.mdpi.com/2073-4409/10/12/3464

Internet

https://www.mdpi.com/2073-4409/10/12/3464

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