Viral and Cellular Factors Contributing to the Hematogenous Dissemination of Human Cytomegalovirus via Polymorphonuclear Leukocytes

Viral and Cellular Factors Contributing to the Hematogenous Dissemination of Human Cytomegalovirus via Polymorphonuclear Leukocytes

Polymorphonuclear leukocytes (PMNs) presumably transmit human cytomegalovirus (HCMV) between endothelial cells in blood vessels and thereby facilitate spread to peripheral organs. We aimed to identify viral components that contribute to PMN-mediated transmission and test the hypothesis that cellular...

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Bibliographic Details
Main Authors: Berenike Braun, Kerstin Laib Sampaio, Anna K. Kuderna, Miriam Widmann, Christian Sinzger
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Viruses
Subjects:
human cytomegalovirus
clinical isolates
hematogenous dissemination
herpesvirus entry
entry inhibitors
Online Access:https://www.mdpi.com/1999-4915/14/7/1561

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https://www.mdpi.com/1999-4915/14/7/1561

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