Ion exchange chromatography as a simple and scalable method to isolate biologically active small extracellular vesicles from conditioned media.

In the last few years, extracellular vesicles (EVs) have become of great interest due to their potential as biomarkers, drug delivery systems, and, in particular, therapeutic agents. However, there is no consensus on which is the best way to isolate these EVs. The choice of the isolation method depe...

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Bibliographic Details
Main Authors: Ricardo Malvicini, Diego Santa-Cruz, Anna Maria Tolomeo, Maurizio Muraca, Gustavo Yannarelli, Natalia Pacienza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0291589