Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection: an in vitro and in vivo study

Efficacy of EDTA-NS irrigation in eradicating Staphylococcus aureus biofilm-associated infection: an in vitro and in vivo study

Aims: To investigate the efficacy of ethylenediaminetetraacetic acid-normal saline (EDTA-NS) in dispersing biofilms and reducing bacterial infections. Methods: EDTA-NS solutions were irrigated at different durations (1, 5, 10, and 30 minutes) and concentrations (1, 2, 5, 10, and 50 mM) to disrupt...

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Bibliographic Details
Main Authors: Junqing Lin, Jinlong Suo, Bingbo Bao, Haifeng Wei, Tao Gao, Hongyi Zhu, Xianyou Zheng
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2024-01-01
Series:Bone & Joint Research
Subjects:
therapeutic irrigation
biofilm-associated infection
staphylococcus aureus
infections
biofilms
highly cross-linked polyethylene (hxlpe)
rat model
surgical debridement
rifampicin
bacteria
staining
saline
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.131.BJR-2023-0141.R1

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https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.131.BJR-2023-0141.R1

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