Domestication of self-splicing introns during eukaryogenesis: the rise of the complex spliceosomal machinery
Abstract ᅟ The spliceosome is a eukaryote-specific complex that is essential for the removal of introns from pre-mRNA. It consists of five small nuclear RNAs (snRNAs) and over a hundred proteins, making it one of the most complex molecular machineries. Most of this complexity has emerged during euka...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-12-01
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Series: | Biology Direct |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13062-017-0201-6 |