Domestication of self-splicing introns during eukaryogenesis: the rise of the complex spliceosomal machinery

Abstract ᅟ The spliceosome is a eukaryote-specific complex that is essential for the removal of introns from pre-mRNA. It consists of five small nuclear RNAs (snRNAs) and over a hundred proteins, making it one of the most complex molecular machineries. Most of this complexity has emerged during euka...

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Bibliographic Details
Main Authors: Julian Vosseberg, Berend Snel
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Biology Direct
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13062-017-0201-6