Chemotactic migration of T cells towards dendritic cells promotes the detection of rare antigens.

In many immunological processes chemoattraction is thought to play a role in guiding cells to their sites of action. However, based on in vivo two-photon microscopy experiments in the absence of cognate antigen, T cell migration in lymph nodes (LNs) has been roughly described as a random walk. Altho...

Full description

Bibliographic Details
Main Authors: Renske M A Vroomans, Athanasius F M Marée, Rob J de Boer, Joost B Beltman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3499258?pdf=render