Identification of the molecular mechanism and diagnostic biomarkers in the thoracic ossification of the ligamentum flavum using metabolomics and transcriptomics

Identification of the molecular mechanism and diagnostic biomarkers in the thoracic ossification of the ligamentum flavum using metabolomics and transcriptomics

Abstract Background To establish a metabolite fingerprint of ossification of the thoracic ligamentum flavum (OTLF) patients using liquid chromatography-mass spectrometry (LC-MS) in combination with transcriptomic data and explore the potential molecular mechanism of pathogenesis. Results The study c...

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Bibliographic Details
Main Authors: Jiahao Li, Lingjia Yu, Shigong Guo, Yu Zhao
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Molecular and Cell Biology
Subjects:
Ossification of the ligamentum flavum
Uric acid
XDH
Metabolomics
Transcriptomic
Online Access:http://link.springer.com/article/10.1186/s12860-020-00280-3

Internet

http://link.springer.com/article/10.1186/s12860-020-00280-3

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