A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection

A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection

Abstract Background Varicella zoster virus (VZV), which is a human restricted alpha-herpesvirus, causes varicella (chickenpox) and zoster (shingles). The subsequent post-herpetic neuralgia (PHN) due to VZV infection is excruciating for most patients. Thus, developing specific therapeutics against VZ...

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Bibliographic Details
Main Authors: Jiawei Pei, Ye Tian, Wei Ye, Jiangfan Han, Yamei Dang, Tong Cheng, Wei Wang, Yipu Zhao, Weiliang Ye, Shuyuan Huangfu, Yu Li, Fanglin Zhang, Yingfeng Lei, Airong Qian
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cell & Bioscience
Subjects:
Varicella zoster virus (VZV)
Recombinant siRNA
r/si-ORF7
Flexible nano-liposomes
3D human epidermal skin model
Online Access:https://doi.org/10.1186/s13578-023-01108-1

Internet

https://doi.org/10.1186/s13578-023-01108-1

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