Gypenosides ameliorate ductular reaction and liver fibrosis via inhibition of hedgehog signaling

Gypenosides ameliorate ductular reaction and liver fibrosis via inhibition of hedgehog signaling

Backgroud and aims: Ductular reaction (DR) is a common pathological change and thought to have a key role in the pathogenesis and progression of liver fibrosis. Our previous study reported Gypenosides (GPs) ameliorated liver fibrosis, however, the anti-fibrotic mechanisms of GPs are still unclear.Me...

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Bibliographic Details
Main Authors: Yonghong Hu, Xiaoli He, Xiaoxi Zhou, Yue Liang, Yadong Fu, Linzhang Zhang, Jing Fang, Wei Liu, Gaofeng Chen, Yongping Mu, Hua Zhang, Hong Cai, Chenghai Liu, Ping Liu, Jiamei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
gypenosides
liver fibrosis
ductular reaction
hedgehog signaling
NPLC0393
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1033103/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1033103/full

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