Molecular mechanisms of congenital heart disease in down syndrome

Down syndrome (DS), as a typical genomic aneuploidy, is a common cause of various birth defects, among which is congenital heart disease (CHD). 40–60% neonates with DS have some kinds of CHD. However, the molecular pathogenic mechanisms of DS associated CHD are still not fully understood. This revie...

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Bibliographic Details
Main Authors: Hui Zhang, Lingjuan Liu, Jie Tian
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-12-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304219300443