Sulforaphane targets cancer stemness and tumor initiating properties in oral squamous cell carcinomas via miR-200c induction

Sulforaphane targets cancer stemness and tumor initiating properties in oral squamous cell carcinomas via miR-200c induction

Background/Purpose: Cancer stem cells (CSCs) are deemed as the driving force of tumorigenesis in oral squamous cell carcinomas (OSCCs). In this study, we investigated the chemotherapeutic effect of sulforaphane, a dietary component from broccoli sprouts, on targeting OSCC-CSCs. Methods: The effect o...

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Bibliographic Details
Main Authors: Chia-Ming Liu, Chih-Yu Peng, Yi-Wen Liao, Ming-Yi Lu, Meng-Lun Tsai, Jung-Chun Yeh, Chuan-Hang Yu, Cheng-Chia Yu
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Journal of the Formosan Medical Association
Subjects:
cancer stemness
oral squamous cell carcinomas
sulforaphane
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664616000280

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http://www.sciencedirect.com/science/article/pii/S0929664616000280

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