Identification of Potential Anti-Neuroinflammatory Inhibitors from Antarctic Fungal Strain <i>Aspergillus</i> sp. SF-7402 via Regulating the NF-κB Signaling Pathway in Microglia

Identification of Potential Anti-Neuroinflammatory Inhibitors from Antarctic Fungal Strain <i>Aspergillus</i> sp. SF-7402 via Regulating the NF-κB Signaling Pathway in Microglia

Microglia play a significant role in immune defense and tissue repair in the central nervous system (CNS). Microglial activation and the resulting neuroinflammation play a key role in the pathogenesis of neurodegenerative disorders. Recently, inflammation reduction strategies in neurodegenerative di...

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Bibliographic Details
Main Authors: Thao Quyen Cao, Zhiming Liu, Linsha Dong, Hwan Lee, Wonmin Ko, Le Ba Vinh, Nguyen Quoc Tuan, Youn-Chul Kim, Jae Hak Sohn, Joung Han Yim, Dong-Sung Lee, Hyuncheol Oh
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
Antarctica
fungi metabolites
neuroinflammation
BV2 cells
sterigmatocystin
NF-κB
Online Access:https://www.mdpi.com/1420-3049/27/9/2851

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https://www.mdpi.com/1420-3049/27/9/2851

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