Assessment of Immune and Clinical Response in Patients with Mucosal Leishmaniasis Treated with Pentavalent Antimony and Pentoxifylline

Assessment of Immune and Clinical Response in Patients with Mucosal Leishmaniasis Treated with Pentavalent Antimony and Pentoxifylline

Mucosal leishmaniasis (ML) is a severe form of tegumentary leishmaniasis associated with a persistent inflammatory response. High levels of TNF, IFN-γ, CXCL9 and CXCL10 are found in ML patients, and the association of pentoxifylline with antimony is more effective in decreasing the healing time in M...

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Bibliographic Details
Main Authors: Carolina Cincura, Rubia S. Costa, Clara Monica F. De Lima, Jamary Oliveira-Filho, Paulo Novis Rocha, Edgar M. Carvalho, Marcus M. Lessa
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Tropical Medicine and Infectious Disease
Subjects:
chemokine CXCL9
chemokine CXCL10
TNF
IFN-γ
disease stage
severity
Online Access:https://www.mdpi.com/2414-6366/7/11/383

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https://www.mdpi.com/2414-6366/7/11/383

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