Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer

Tertiary lymphoid structures (TLS) are lymph node-like aggregates that can form in association with chronic inflammation or cancer. Mature TLS are organized into B and T cell zones, and are not encapsulated but include all cell types necessary for eliciting an adaptive immune response. TLS have been...

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Bibliographic Details
Main Authors: Alessandra Vaccaro, Tiarne van de Walle, Mohanraj Ramachandran, Magnus Essand, Anna Dimberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1275378/full