Characterization of a Bacterial Kinase That Phosphorylates Dihydrosphingosine to Form dhS1P

ABSTRACT Like other members of the phylum Bacteroidetes, the oral anaerobe Porphyromonas gingivalis synthesizes a variety of sphingolipids, similar to its human host. Studies have shown that synthesis of these lipids (dihydroceramides [DHCs]) is involved in oxidative stress resistance, the survival...

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Bibliographic Details
Main Authors: Dev K. Ranjit, Zachary D. Moye, Fernanda G. Rocha, Gregory Ottenberg, Frank C. Nichols, Hey-Min Kim, Alejandro R. Walker, Frank C. Gibson, Mary E. Davey
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00002-22