Transcriptomic Analysis of the Effect of Torin-2 on the Central Nervous System of <i>Drosophila melanogaster</i>

Transcriptomic Analysis of the Effect of Torin-2 on the Central Nervous System of <i>Drosophila melanogaster</i>

Torin-2, a synthetic compound, is a highly selective inhibitor of both TORC1 and TORC2 (target of rapamycin) complexes as an alternative to the well-known immunosuppressor, geroprotector, and potential anti-cancer natural compound rapamycin. Torin-2 is effective at hundreds of times lower concentrat...

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Bibliographic Details
Main Authors: Yulia S. Vershinina, George S. Krasnov, David G. Garbuz, Mikhail V. Shaposhnikov, Maria S. Fedorova, Elena A. Pudova, Irina V. Katunina, Alexey B. Kornev, Nadezhda V. Zemskaya, Alexander A. Kudryavtsev, Elizaveta V. Bulavkina, Anna A. Matveeva, Natalia S. Ulyasheva, Zulfiya G. Guvatova, Artemiy A. Anurov, Alexey A. Moskalev, Anna V. Kudryavtseva
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
RNA-Seq
TOR
neurodegeneration
neuroprotection
Torin-2
Online Access:https://www.mdpi.com/1422-0067/24/10/9095

Internet

https://www.mdpi.com/1422-0067/24/10/9095

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