Synthesis and biological evaluation of 5-substituted derivatives of benzimidazole

Synthesis and biological evaluation of 5-substituted derivatives of benzimidazole

Series of eight novel 5-substituted derivatives of benzimidazole were synthesized by condensation of corresponding diamine with ethyl-4-[4-(2-chlorophenyl)piperazin-1-yl] butanoate in refluxing 4N hydrochloric acid. In vitro antibacterial activity against ten strains namely, Bacillus sub...

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Bibliographic Details
Main Authors: Vasić Vesna P., Penjišević Jelena Z., Novaković Irena T., Šukalović Vladimir V., Andrić Deana B., Kostić-Rajačić Slađana V.
Format: Article
Language:English
Published: Serbian Chemical Society 2014-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
arylpiperazines
benzimidazoles
antibacterial activity
antifungal activity
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2014/0352-51391300058V.pdf

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http://www.doiserbia.nb.rs/img/doi/0352-5139/2014/0352-51391300058V.pdf

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