An evaluation of the combination effect of zoledronate and chemotherapeutic agents in canine osteosarcoma cells

IntroductionOsteosarcoma (OSA) is an aggressive form of bone cancer in both dogs and humans. The treatment options for metastatic (stage III) OSA are currently limited and the prognosis is poor. Zoledronate, a second generation amino-bisphosphonate, is commonly used for palliation of cancer induced...

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Bibliographic Details
Main Authors: Yoshimi Iwaki, Stephanie E. S. Lindley, Noelle Bergman, Bruce F. Smith, Satyanarayana R. Pondugula
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Veterinary Science
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Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2024.1327377/full