Human photoreceptors switch from autonomous axon extension to cell-mediated process pulling during synaptic marker redistribution

Summary: Photoreceptors (PRs) are the primary visual sensory cells, and their loss leads to blindness that is currently incurable. Although cell replacement therapy holds promise, success is hindered by our limited understanding of PR axon growth during development and regeneration. Here, we generat...

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Bibliographic Details
Main Authors: Sarah K. Rempel, Madalynn J. Welch, Allison L. Ludwig, M. Joseph Phillips, Yochana Kancherla, Donald J. Zack, David M. Gamm, Timothy M. Gómez
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722005988