Bimolecular fluorescence complementation; lighting-up tau-tau interaction in living cells.

Abnormal tau aggregation is a pathological hallmark of many neurodegenerative disorders and it is becoming apparent that soluble tau aggregates play a key role in neurodegeneration and memory impairment. Despite this pathological importance, there is currently no single method that allows monitoring...

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Bibliographic Details
Main Authors: Hyejin Tak, Md Mamunul Haque, Min Jung Kim, Joo Hyun Lee, Ja-Hyun Baik, Youngsoo Kim, Dong Jin Kim, Regis Grailhe, Yun Kyung Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3847076?pdf=render