MIR155HG Plays a Bivalent Role in Regulating Innate Antiviral Immunity by Encoding Long Noncoding RNA-155 and microRNA-155-5p

MIR155HG Plays a Bivalent Role in Regulating Innate Antiviral Immunity by Encoding Long Noncoding RNA-155 and microRNA-155-5p

ABSTRACT MIR155HG encodes a precursor RNA of microRNA-155 (miRNA-155). We previously identified this RNA also as a long noncoding RNA (lncRNA) that we call lncRNA-155. To define the functions of miRNA-155 and lncRNA-155, we generated miRNA-155 knockout (KO) mice lacking only 19 bp of the miRNA-155 c...

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Bibliographic Details
Main Authors: Kul Raj Rai, Yuan Liao, Mengjuan Cai, Haori Qiu, Faxin Wen, Min Peng, Song Wang, Shasha Liu, Guijie Guo, Xiaojuan Chi, Mohamed Maarouf, Yuhai Chen, Shile Huang, Ji-Long Chen
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mBio
Subjects:
MIR155HG
lncRNA-155
miRNA-155-5p
influenza A virus
STAT1
immune response
Online Access:https://journals.asm.org/doi/10.1128/mbio.02510-22

Internet

https://journals.asm.org/doi/10.1128/mbio.02510-22

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