Novel Putative Positive Modulators of α4β2 nAChRs Potentiate Nicotine Reward-Related Behavior

Novel Putative Positive Modulators of α4β2 nAChRs Potentiate Nicotine Reward-Related Behavior

The popular tobacco and e-cigarette chemical flavorant (−)-menthol acts as a nonselective, noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs), and contributes to multiple physiological effects that exacerbates nicotine addiction-related behavior. Menthol is classically known as...

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Bibliographic Details
Main Authors: Skylar Y. Cooper, Austin T. Akers, Velvet Blair Journigan, Brandon J. Henderson
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
allosteric
nicotine
nicotinic receptor
conditioned place preference
Online Access:https://www.mdpi.com/1420-3049/26/16/4793

Internet

https://www.mdpi.com/1420-3049/26/16/4793

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