Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions

Abstract Background During embryogenesis, the developmental potential of initially pluripotent cells becomes progressively restricted as they transit to lineage restricted states. The pluripotent cells of Xenopus blastula-stage embryos are an ideal system in which to study cell state transitions dur...

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Bibliographic Details
Main Authors: Kristin Johnson, Simon Freedman, Rosemary Braun, Carole LaBonne
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-022-08953-3