Transcriptomic Analysis of the Activity of a Novel Polymyxin against <named-content content-type="genus-species">Staphylococcus aureus</named-content>

ABSTRACT Polymyxin B and colistin are exclusively active against Gram-negative pathogens and have been used in the clinic as a last-line therapy. In this study, we investigated the antimicrobial activity of a novel polymyxin, FADDI-019, against Staphylococcus aureus. MIC and time-kill assays were em...

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Bibliographic Details
Main Authors: Jinxin Zhao, Soon-Ee Cheah, Kade D. Roberts, Roger L. Nation, Philip E. Thompson, Tony Velkov, Zongjun Du, Matthew D. Johnson, Jian Li
Format: Article
Language:English
Published: American Society for Microbiology 2016-08-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00119-16