Identification of a novel binding inhibitor that blocks the interaction between hSCARB2 and VP1 of enterovirus 71

Identification of a novel binding inhibitor that blocks the interaction between hSCARB2 and VP1 of enterovirus 71

Enterovirus 71 (EV-A71) infection causes severe hand-foot-and-mouth disease that leads to cardiopulmonary complications and death in young children under 5 years of age. Although there are available vaccines for EV-A71 C4, however, there are no efficient drugs for severe cases. Thus, there is an urg...

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Bibliographic Details
Main Authors: Qi Tang, Zhichao Xu, Fan Zhang, Yang Cai, Yinuo Chen, Baojing Lu, Hai-bing Zhou, Ke Lan, Shuwen Wu
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Cell Insight
Subjects:
EV-A71
Enterovirus
DAAs
VP1
PTC-209HBr
Pirodavir
Online Access:http://www.sciencedirect.com/science/article/pii/S277289272200013X

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http://www.sciencedirect.com/science/article/pii/S277289272200013X

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