25-hydroxyvitamin D3 inhibits oxidative stress and ferroptosis in retinal microvascular endothelial cells induced by high glucose through down-regulation of miR-93

Abstract Background The decrease of vitamin D plays a critical role in diabetes mellitus (DM)-induced oxidative stress and vascular endothelial injury. Therefore, we investigated the effect and mechanism of 25-hydroxyvitamin D3 (25 (OH) D3) on oxidative stress and ferroptosis induced by high glucose...

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Bibliographic Details
Main Authors: Dongmei Zhan, Juan Zhao, Qin Shi, Juan Lou, Weiling Wang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Ophthalmology
Subjects:
Online Access:https://doi.org/10.1186/s12886-022-02762-8