Rapid development of double-hit mRNA antibody cocktail against orthopoxviruses

Abstract The Orthopoxvirus genus, especially variola virus (VARV), monkeypox virus (MPXV), remains a significant public health threat worldwide. The development of therapeutic antibodies against orthopoxviruses is largely hampered by the high cost of antibody engineering and manufacturing processes....

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Bibliographic Details
Main Authors: Hang Chi, Suo-Qun Zhao, Ru-Yi Chen, Xing-Xing Suo, Rong-Rong Zhang, Wen-Hui Yang, Dong-Sheng Zhou, Min Fang, Bo Ying, Yong-Qiang Deng, Cheng-Feng Qin
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-024-01766-8