Anticancer and Structure Activity Relationship of Non-Symmetrical Choline Kinase Inhibitors

Anticancer and Structure Activity Relationship of Non-Symmetrical Choline Kinase Inhibitors

Choline kinase inhibitors are an outstanding class of cytotoxic compounds useful for the treatment of different forms of cancer since aberrant choline metabolism is a feature of neoplastic cells. Here, we present the most in-depth structure-activity relationship studies of an interesting series of n...

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Bibliographic Details
Main Authors: Santiago Schiaffino-Ortega, Elena Mariotto, Pilar María Luque-Navarro, María Kimatrai-Salvador, Pablo Rios-Marco, Ramon Hurtado-Guerrero, Carmen Marco, María Paz Carrasco-Jimenez, Giampietro Viola, Luisa Carlota López-Cara
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
antitumoral drug
choline kinase inhibition
choline uptake
Online Access:https://www.mdpi.com/1999-4923/13/9/1360

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https://www.mdpi.com/1999-4923/13/9/1360

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