Inhibition of Very Long Chain Fatty Acids Synthesis Mediates PI3P Homeostasis at Endosomal Compartments

Inhibition of Very Long Chain Fatty Acids Synthesis Mediates PI3P Homeostasis at Endosomal Compartments

A main characteristic of sphingolipids is the presence of a very long chain fatty acid (VLCFA) whose function in cellular processes is not yet fully understood. VLCFAs of sphingolipids are involved in the intracellular traffic to the vacuole and the maturation of early endosomes into late endosomes...

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Bibliographic Details
Main Authors: Yoko Ito, Nicolas Esnay, Louise Fougère, Matthieu Pierre Platre, Fabrice Cordelières, Yvon Jaillais, Yohann Boutté
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
very-long chain fatty acids
phosphatidylinositol-3-phosphate
trans-Golgi network
multivesicular bodies
endosomes
vacuole
Online Access:https://www.mdpi.com/1422-0067/22/16/8450

Internet

https://www.mdpi.com/1422-0067/22/16/8450

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