Implementation of Isavuconazole in a Fluorescence-Based High-Performance Liquid Chromatography Kit Allowing Simultaneous Detection of All Four Currently Licensed Mold-Active Triazoles

Implementation of Isavuconazole in a Fluorescence-Based High-Performance Liquid Chromatography Kit Allowing Simultaneous Detection of All Four Currently Licensed Mold-Active Triazoles

ABSTRACT Isavuconazole (ISZ) is a newly available broad-spectrum triazole agent recently approved for the treatment of both invasive aspergillosis and mucormycosis. The aim of this study was to develop a simple and reliable method for therapeutic drug monitoring (TDM) of ISZ in human plasma samples....

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Bibliographic Details
Main Authors: René Jørgensen, Siri Rytcher Andersen, Karen Marie Thyssen Astvad, Maiken Cavling Arendrup
Format: Article
Language:English
Published: American Society for Microbiology 2017-06-01
Series:mSphere
Subjects:
HPLC
isavuzonazole
TDM
therapeutic drug monitoring
fluorescence detection
triazoles
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00098-17

Internet

https://journals.asm.org/doi/10.1128/mSphere.00098-17

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