Integrin αvβ3 Signaling in Tumor-Induced Bone Disease

Tumor-induced bone disease is common among patients with advanced solid cancers, especially those with breast, prostate, and lung malignancies. The tendency of these cancers to metastasize to bone and induce bone destruction is, in part, due to alterations in integrin expression and signaling. Subst...

Full description

Bibliographic Details
Main Authors: Kristin A. Kwakwa, Julie A. Sterling
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/9/7/84