The Role of Promyelocytic Leukemia Zinc Finger (PLZF) and Glial-Derived Neurotrophic Factor Family Receptor Alpha 1 (GFRα1) in the Cryopreservation of Spermatogonia Stem Cells

The Role of Promyelocytic Leukemia Zinc Finger (PLZF) and Glial-Derived Neurotrophic Factor Family Receptor Alpha 1 (GFRα1) in the Cryopreservation of Spermatogonia Stem Cells

The cryopreservation of spermatogonia stem cells (SSCs) has been widely used as an alternative treatment for infertility. However, cryopreservation itself induces cryoinjury due to oxidative and osmotic stress, leading to reduction in the survival rate and functionality of SSCs. Glial-derived neurot...

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Bibliographic Details
Main Authors: Asma’ ‘Afifah Shamhari, Nur Erysha Sabrina Jefferi, Zariyantey Abd Hamid, Siti Balkis Budin, Muhd Hanis Md Idris, Izatus Shima Taib
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
antioxidant
cryopreservation
infertility
spermatogonia
spermatogenesis
GFRα1
Online Access:https://www.mdpi.com/1422-0067/24/3/1945

Internet

https://www.mdpi.com/1422-0067/24/3/1945

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