Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein.

Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein.

Interferon-γ (IFN-γ) represents one of the most important innate immunity responses in a host to combat infections of many human viruses including human herpesviruses. Human N-myc interactor (Nmi) protein, which has been shown to interact with signal transducer and activator of transcription (STAT)...

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Bibliographic Details
Main Authors: Linyuan Feng, Jingxue Sheng, Gia-Phong Vu, Yujun Liu, Chingman Foo, Songbin Wu, Phong Trang, Marco Paliza-Carre, Yanhong Ran, Xiaoping Yang, Xu Sun, Zemin Deng, Tianhong Zhou, Sangwei Lu, Hongjian Li, Fenyong Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5805366?pdf=render

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http://europepmc.org/articles/PMC5805366?pdf=render

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