CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer.

CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer.

The CBFB gene is frequently mutated in several types of solid tumors. Emerging evidence suggests that CBFB is a tumor suppressor in breast cancer. However, our understanding of the tumor suppressive function of CBFB remains incomplete. Here, we analyze genetic interactions between mutations of CBFB...

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Bibliographic Details
Main Authors: Navdeep Malik, Hualong Yan, Howard H Yang, Gamze Ayaz, Wendy DuBois, Yu-Chou Tseng, Young-Im Kim, Shunlin Jiang, Chengyu Liu, Maxwell Lee, Jing Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009553

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https://doi.org/10.1371/journal.pgen.1009553

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