ERK pathway activation bidirectionally affects visual recognition memory and synaptic plasticity in the perirhinal cortex

ERK pathway activation bidirectionally affects visual recognition memory and synaptic plasticity in the perirhinal cortex

ERK 1,2 pathway mediates experience-dependent gene transcription in neurons and several studies have identified its pivotal role in experience-dependent synaptic plasticity and in forms of long term memory involving hippocampus, amygdala or striatum. The perirhinal cortex (PRHC) plays an essential r...

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Bibliographic Details
Main Authors: Davide eSilingardi, Andrea eAngelucci, Roberto eDe Pasquale, Marco eBorsotti, Giovanni eSquitieri, Riccardo eBrambilla, Elena ePutignano, Tommaso ePizzorusso, Nicoletta eBerardi
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
synaptic plasticity
recognition memory
2
perirhinal cortex
ERK1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00084/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00084/full

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