Elevated Levels of Soluble Axl (sAxl) Regulates Key Angiogenic Molecules to Induce Placental Endothelial Dysfunction and a Preeclampsia-Like Phenotype

Elevated Levels of Soluble Axl (sAxl) Regulates Key Angiogenic Molecules to Induce Placental Endothelial Dysfunction and a Preeclampsia-Like Phenotype

Preeclampsia (PE), a severe pregnancy-specific syndrome, is characterized by impaired placental angiogenesis. Although the pathogenesis of this condition remains largely unclear, vascular systemic endothelial injury is thought to be the common contributing factor. Soluble Axl (sAxl), a biomarker of...

Full description

Bibliographic Details
Main Authors: Shunping Gui, Shengping Zhou, Min Liu, Yanping Zhang, Linbo Gao, Tao Wang, Rong Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
preeclampsia
endothelial dysfunction
placenta
sAxl
rat
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.619137/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.619137/full

Similar Items