Inhibition of 6-Phosphogluconate Dehydrogenase Reverses Epirubicin Resistance Through Metabolic Reprograming in Triple-Negative Breast Cancer Cells

At present, chemotherapy is the most effective strategy for treating triple-negative breast cancer (TNBC), but its efficacy was limited by the development of chemo-resistance. The exact mechanism of chemoresistance still remains unclear. This study aims to examine whether 6-phosphogluconate dehydrog...

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Bibliographic Details
Main Authors: Jiali Xu MM, Guosheng Ren MD, Qiao Cheng MD
Format: Article
Language:English
Published: SAGE Publishing 2023-08-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/15330338231190737