pH-triggered dynamic erosive small molecule chlorambucil nano-prodrugs mediate robust oral chemotherapy

pH-triggered dynamic erosive small molecule chlorambucil nano-prodrugs mediate robust oral chemotherapy

Currently, the dynamic erosive small molecule nano-prodrug is of great demand for oral chemotherapy, owing to its precise structure, high drug loading and improved oral bioavailability via overcoming various physiologic barriers in gastrointestinal tract, blood circulation and tumor tissues compared...

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Bibliographic Details
Main Authors: Xin Liu, Zhexiang Wang, Xiaodie Ren, Xinyang Chen, Jinjin Tao, Yuanhui Guan, Xuefeng Yang, Rupei Tang, Guoqing Yan
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Nano-prodrugs
pH sensitivity
Size transition
Oral chemotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087623000594

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http://www.sciencedirect.com/science/article/pii/S1818087623000594

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