Control of the signaling role of PtdIns(4)P at the plasma membrane through H2O2-dependent inactivation of synaptojanin 2 during endocytosis

Control of the signaling role of PtdIns(4)P at the plasma membrane through H2O2-dependent inactivation of synaptojanin 2 during endocytosis

Phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] is implicated in various processes, including hormone-induced signal transduction, endocytosis, and exocytosis in the plasma membrane. However, how H2O2 accumulation regulates the levels of PtdIns(4,5)P2 in the plasma membrane in cells stimulated...

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Bibliographic Details
Main Authors: Su In Jo, Suree Kim, Jung Mi Lim, Sue Goo Rhee, Bo-Gyeong Jeong, Sun-Shin Cha, Jae-Byum Chang, Dongmin Kang
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Redox Biology
Subjects:
Synaptojanin (synj)
Phosphatidylinositol 4-phosphate [PtdIns(4)P]
Protein oxidation
Hydrogen peroxide
Endocytosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724000739

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http://www.sciencedirect.com/science/article/pii/S2213231724000739

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