Risk-benefit analysis of isoniazid monotherapy to prevent tuberculosis in patients with rheumatic diseases exposed to prolonged, high-dose glucocorticoids.

<h4>Objective</h4>To investigate the incidence of tuberculosis (TB) in patients with rheumatic diseases receiving high-dose glucocorticoids and to evaluate the preventive effect of isoniazid (INH).<h4>Methods</h4>This study included 1618 treatment episodes of prolonged (≥4 we...

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Bibliographic Details
Main Authors: Jun Won Park, Jeffrey R Curtis, Hajeong Lee, Jung-Kyu Lee, Yeong Wook Song, Eun Bong Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244239