Chitotriosidase 1 in the cerebrospinal fluid as a putative biomarker for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) progression

Chitotriosidase 1 in the cerebrospinal fluid as a putative biomarker for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) progression

Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an inflammatory neurodegenerative disease that affects motor, urinary, intestinal, and sensory functions. Typically, HAM/TSP is slowly progressive, but it may vary from limited motor disability...

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Main Authors: Yago Côrtes Pinheiro Gomes, Nicole Lardini Freitas, Flávia Santos Souza, Vanessa Sandim, Denise Abreu Pereira, Fábio César Sousa Nogueira, Juliana Echevarria-Lima, Ana Claudia Celestino Bezerra Leite, Marco Antonio Sales Dantas Lima, Marcus Tulius Teixeira Silva, Abelardo Queiroz Campos Araújo, Ana Carolina Paulo Vicente, Otávio Melo Espíndola
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
HTLV-1
HAM/TSP
biomarkers
cerebrospinal fluid
neurodegeneration
chitotriosidase 1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.949516/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.949516/full

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