Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype

Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype

Omalizumab is a monoclonal antibody indicated for the treatment of severe uncontrolled asthma with an allergic phenotype. Its effectiveness could be influenced by clinical variables and single nucleotide polymorphisms (SNPs) in one or more of the genes involved in the mechanism of action and process...

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Bibliographic Details
Main Authors: Susana Rojo-Tolosa, José Antonio Sánchez-Martínez, Laura Elena Pineda-Lancheros, José María Gálvez-Navas, María Victoria González-Gutiérrez, Gonzalo Jiménez-Gálvez, Cristina Pérez-Ramírez, Concepción Morales-García, Alberto Jiménez-Morales
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
severe uncontrolled asthma
omalizumab
effectiveness
polymorphisms
Online Access:https://www.mdpi.com/1422-0067/24/8/7029

Internet

https://www.mdpi.com/1422-0067/24/8/7029

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