The Important Role of Protein Kinases in the p53 Sestrin Signaling Pathway

p53, a crucial tumor suppressor and transcription factor, plays a central role in the maintenance of genomic stability and the orchestration of cellular responses such as apoptosis, cell cycle arrest, and DNA repair in the face of various stresses. Sestrins, a group of evolutionarily conserved prote...

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Bibliographic Details
Main Authors: Karsten Gülow, Deniz Tümen, Claudia Kunst
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/22/5390