Role of N-acetylkynurenine in mediating the effect of gut microbiota on urinary tract infection: a Mendelian randomization study

Role of N-acetylkynurenine in mediating the effect of gut microbiota on urinary tract infection: a Mendelian randomization study

IntroductionThis study explored the causal connections between gut microbiota (GM), urinary tract infection (UTI), and potential metabolite mediators using Mendelian randomization (MR).MethodsWe utilized summary statistics from the most comprehensive and extensive genome-wide association studies (GW...

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Bibliographic Details
Main Authors: Yining He, Chao Han, Chengjuan Li, Xiaofan Yin, Jiawen Wang, Lina Gu, Ruxue Yan, Buhui Liu, Xuan Zhou, Weiming He
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Microbiology
Subjects:
gut microbiota
urinary tract infection
blood metabolites
N-acetylkynurenine
Mendelian randomization analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1384095/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2024.1384095/full

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