Utility of a buccal swab point-of-care test for the IFNL4 genotype in the era of direct acting antivirals for hepatitis C virus.

Utility of a buccal swab point-of-care test for the IFNL4 genotype in the era of direct acting antivirals for hepatitis C virus.

<h4>Background</h4>The CC genotype of the IFNL4 gene is known to be associated with increased Hepatitis C (HCV) cure rates with interferon-based therapy and may contribute to cure with direct acting antivirals. The Genedrive® IFNL4 is a CE marked Point of Care (PoC) molecular diagnostic...

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Bibliographic Details
Main Authors: Aminata Sy, Leanne McCabe, Emma Hudson, Azim M Ansari, Vincent Pedergnana, Shang-Kuan Lin, S Santana, Marzia Fiorino, Aftab Ala, Ben Stone, M Smith, Mark Nelson, Stephen T Barclay, Stuart McPherson, Stephen D Ryder, Jane Collier, Eleanor Barnes, Ann Sarah Walker, Sarah L Pett, Graham Cooke, STOP-HCV-1 trial team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0280551

Internet

https://doi.org/10.1371/journal.pone.0280551

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